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Multiple Sclerosis - Symptoms And Treatment

Multiple Sclerosis(MS)also known as disseminated sclerosis or encephalomyelitis disseminata is a chronic, inflammatory, demyelinating disease that affects the central nervous system (CNS). Multiple sclerosis affects neurons, the cells of the brain and spinal cord that carry information, create thought and perception, and allow the brain to control the body. Surrounding and protecting some of these neurons is a fatty layer known as the myelin sheath, which helps neurons carry electrical signals. MS causes gradual destruction of myelin (demyelination) and transection of neuron axons in patches throughout the brain and spinal cord. The name multiple sclerosis refers to the multiple scars (or scleroses) on the myelin sheaths.

Causes

Multiple sclerosis is an autoimmune disease, meaning its cause is an attack by the body's own immune system. For unknown reasons, immune cells attack and destroy the myelin sheath that insulates neurons in the brain and spinal cord. This myelin sheath, created by other brain cells called glia, speeds transmission and prevents electrical activity in one cell from short-circuiting to another cell. Disruption of communication between the brain and other parts of the body prevent normal passage of sensations and control messages, leading to the symptoms of MS. The demyelinated areas appear as plaques, small round areas of gray neuron without the white myelin covering. The progression of symptoms in MS is correlated with development of new plaques in the portion of the brain or spinal cord controlling the affected areas. Because there appears to be no pattern in the appearance of new plaques, the progression of MS can be unpredictable.

However, the specific causes of multiple sclerosis are unfortunately unknown. This illustrates the importance to conduct medical trials to attempt to discover the exact causes of the disease. Clinical trials and clinical trial participants are vital to the progress of finding a treatment for multiple sclerosis.

Signs and Symptoms

The hallmark of multiple sclerosis is unpredictable periods of exacerbation, remission, and progression. Initial symptoms of MS may be brief and mild. The first serious attack usually lasts weeks or months and occurs between the ages of 20 and 40.

Balance and equilibrium abnormalities (e.g., dizziness, vertigo, uncoordinated movements, tremor)
Bladder and bowel dysfunction (e.g., urgency, incontinence, nocturia, constipation)
Behavioral changes (e.g., mood swings, depression)

Treatment for Multiple Sclerosis

Currently there is no cure for MS in conventional medicine. However, there are treatments available that may slow its progression and alleviate associated symptoms. Some cures are reported in alternative medicine literature.

Drug therapies—Medications that target the body's immune system may decrease the frequency and duration of attacks. These medications can be used on a long-term basis and also to treat specific attacks. Additional medications may be prescribed for other symptoms, such as pain or depression.

Additional therapies—Because MS may affect the patient's ability to perform self-care and other activities of daily living, treatment may also include referral to specialists for physical and occupational therapy.

Currently, there is no cure for Multiple Sclerosis but there is a wide variety of medicines that can reduce the frequency and severity of attacks. Since all medications have some down-side effects, your doctor can help you decide what you need based on the severity of your disease.

By: User name - Peter Hutch

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