acne is one of the most universal forms of skin problems. It affects both men and women usually only during adolescence. However, there are some kinds of acne that are more severe than others and can cause serious damage to the skin.
If acne becomes severe, it can take a long time to heal. Some types of severe acne can also create deep abscesses and scars after the blemishes have healed.
The main form of severe acne vulgaris is known as acne conglobata. In acne conglobata, infected nodules appear around comedones. The nodules become more inflamed and spread deep below the skin surface. When these nodules burst, they leave deep scars. Blackheads are very usual in this type of acne. It can appear on buttocks, face, trunk, etc. The treatment of acne conglobata is usually done with isotretinoin.
Other insidious kinds of acne are acne fulminans and gram-negative folliculitis. If acne quickly flares up leaving inflammation, ulcers, and fever, it is called acne fulminans. This is usually treated with steroids. Gram-negative folliculitis, on the other hand, is a harsh form of folliculitis that harms the hair follicle and infects the pore. Isotretinoin is the treatment of choice for this type of skin problem.
Any acne condition that keeps flaring up instead of settling down can become a form of severe acne. One of the main consequences of severe acne can be deep acne scars as well as swelling, redness and irritation. If you suffer from any form of severe acne, you should be under the care of a doctor.
The Treatment
When dealing with acne skin care, the best treatment methodology is to treat as many of the causes as possible.
Excessive Sebum Production
Exaggerated sebum secretion begins in puberty due to hormonal changes. The rising levels of androgens, the major sebotrophic hormones, start to elevate sebum secretion. However, while androgenic stimulation is crucial in the pathogenesis of acne, the typical acne sufferer does not have major endocrine abnormalities. Hormonal therapy is not indicated in the initial treatment of mild to moderate acne, although females who need oral contraception can be candidates for anti-androgen therapy early in the course of treatment.
Abnormal Desquamation of the Follicular Epithelium
In acne, keratinocytes hyperproliferate and gather within the sebaceous follicle. As these aberrantly discarded cells gather in the sebaceous follicle, they promote microcomedo appearance. The microcomedo is the precursor to all acne lesions and is present in 4 out of 5 acne papules but is not evident to the unaided eye. However, as the already blocked follicle begins to fill with lipids, microbes and cell fragments, the microcomedo progresses to open or closed comedones (blackheads and whiteheads, respectively), both of which are non-inflammatory blemishes. If P. acnes proliferate, inflammatory elements are generated and inflammatory papules and pustules occur.
Bacterial Growth
With acne problems, the microenvironment of the follicle is conducive to the population of P. acnes. This leads to inflammation and the production of the visible papules and pustules with which acne sufferers typically arrive to dermatologists.
Inflammation
Inflammation in acne appears as a result of hormonal and cellular defensive reactions to the proliferation P. acnes. It has been suggested that changes in sebum secretion or composition harm infundibular keratinocytes leading to the release of interleukin 1a (IL-1a). Also, CD4 lymphocytes and neutrophils are carried to the follicle. Rupture of the follicular conduct leads to the extravasation of lipids, corneocytes and microbes into the skin, causing more inflammation.
Lesions caused by severe forms of acne can now be eliminated thanks to a natural skin care solution that includes one the best healing ingredients that Mother Nature can offer.
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